Meredith M Regan Selected Research

Letrozole (Femara)

2/2021	Cumulative incidence of cardiovascular events under tamoxifen and letrozole alone and in sequence: a report from the BIG 1-98 trial.
1/2021	Genomic Aberrations and Late Recurrence in Postmenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the SOLE Trial.
3/2020	Correction: Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
12/2019	Independent Validation of EarlyR Gene Signature in BIG 1-98: A Randomized, Double-Blind, Phase III Trial Comparing Letrozole and Tamoxifen as Adjuvant Endocrine Therapy for Postmenopausal Women With Hormone Receptor-Positive, Early Breast Cancer.
10/2019	Neoadjuvant Degarelix Versus Triptorelin in Premenopausal Patients Who Receive Letrozole for Locally Advanced Endocrine-Responsive Breast Cancer: A Randomized Phase II Trial.
10/2019	Adjuvant Letrozole and Tamoxifen Alone or Sequentially for Postmenopausal Women With Hormone Receptor-Positive Breast Cancer: Long-Term Follow-Up of the BIG 1-98 Trial.
1/2019	Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1-98.
1/2019	Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
10/2018	Association of Somatic Driver Alterations With Prognosis in Postmenopausal, Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: A Secondary Analysis of the BIG 1-98 Randomized Clinical Trial.
1/2018	Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial.

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Meredith M Regan Research Topics

Disease

78	Breast Neoplasms (Breast Cancer) 03/2022 - 12/2004
61	Neoplasms (Cancer) 01/2021 - 11/2002
46	Prostatic Neoplasms (Prostate Cancer) 12/2020 - 11/2002
9	Renal Cell Carcinoma (Grawitz Tumor) 12/2021 - 01/2005
6	Neoplasm Metastasis (Metastasis) 10/2020 - 01/2005
5	Triple Negative Breast Neoplasms 03/2022 - 06/2010
5	Melanoma (Melanoma, Malignant) 01/2022 - 01/2017
3	Inflammatory Breast Neoplasms 01/2021 - 09/2017
3	Pathologic Complete Response 01/2021 - 10/2013
3	Carcinoma (Carcinomatosis) 01/2018 - 05/2003
3	Malnutrition (Nutritional Deficiencies) 12/2003 - 01/2003
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2020 - 01/2020
2	Arthralgia (Joint Pain) 01/2018 - 07/2015
2	Cystic Fibrosis (Mucoviscidosis) 08/2004 - 02/2004
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2022
1	Pain (Aches) 01/2022
1	Infections 01/2022
1	Wound Infection (Wound Infections) 01/2022
1	Contracture 01/2022
1	Confusion (Bewilderment) 01/2022
1	Circulating Neoplastic Cells 06/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2021
1	Myocardial Ischemia (Ischemic Heart Diseases) 02/2021
1	Overweight 10/2020

Drug/Important Bio-Agent (IBA)

46	Hormones (Hormone)IBA 03/2022 - 05/2003
36	Tamoxifen FDA LinkGeneric 02/2021 - 12/2004
24	Letrozole (Femara)FDA LinkGeneric 02/2021 - 09/2007
22	Prostate-Specific Antigen (Semenogelase)IBA 10/2020 - 01/2003
22	Estrogen ReceptorsIBA 01/2020 - 12/2005
13	AndrogensIBA 01/2019 - 10/2005
12	Progesterone Receptors (Progesterone Receptor)IBA 01/2021 - 11/2006
11	exemestane (Aromasin)FDA Link 01/2020 - 07/2014
10	Aromatase InhibitorsIBA 02/2021 - 08/2009
10	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 07/2006
9	Estrogens (Estrogen)FDA Link 01/2021 - 09/2007
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2013
6	Biological ProductsIBA 01/2021 - 12/2005
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2013 - 02/2004
5	human ERBB2 proteinIBA 01/2021 - 06/2010
5	Androgen Receptors (Androgen Receptor)IBA 12/2020 - 07/2009
5	Formaldehyde (Formol)FDA Link 12/2019 - 09/2013
5	ParaffinIBA 12/2019 - 09/2013
5	Interleukin-2 (IL2)IBA 02/2015 - 01/2005
4	Immune Checkpoint InhibitorsIBA 01/2022 - 12/2019
4	IpilimumabIBA 12/2021 - 01/2019
4	NivolumabIBA 12/2021 - 01/2019
4	RNA (Ribonucleic Acid)IBA 12/2019 - 07/2009
4	Methotrexate (Mexate)FDA LinkGeneric 10/2016 - 03/2008
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2016 - 03/2008
4	SteroidsIBA 11/2011 - 09/2006
3	Progesterone FDA LinkGeneric 01/2021 - 09/2007
3	ErbB Receptors (EGF Receptor)IBA 10/2019 - 01/2016
3	Docetaxel (Taxotere)FDA Link 01/2018 - 12/2006
3	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2017 - 03/2012
3	Lysine (L-Lysine)FDA Link 12/2012 - 01/2003
3	Ketoconazole (Nizoral)FDA LinkGeneric 05/2010 - 09/2006
3	VA 061 (VA061)IBA 09/2007 - 10/2005
2	Fulvestrant (Faslodex)FDA Link 01/2022 - 01/2022
2	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 02/2008
2	AnthracyclinesIBA 01/2021 - 10/2013
2	taxaneIBA 01/2021 - 05/2010
2	Triptorelin Pamoate (Trelstar)FDA Link 10/2019 - 10/2016
2	Phenobarbital (Luminal)FDA Link 10/2019 - 01/2019
2	B7-H1 AntigenIBA 01/2019 - 02/2015
2	Messenger RNA (mRNA)IBA 01/2017 - 10/2013
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2017 - 11/2016
2	Estrogen Receptor alphaIBA 11/2016 - 12/2015
2	Ki-67 Antigen (Ki 67 Antigen)IBA 02/2016 - 02/2008
2	CytokinesIBA 11/2013 - 01/2005
2	Leucine (L-Leucine)FDA Link 12/2012 - 04/2003
2	Proteins (Proteins, Gene)FDA Link 11/2012 - 11/2002
2	thiamine triphosphorate (TTP)IBA 10/2011 - 03/2008
2	SeleniumIBA 01/2011 - 08/2009
2	Fluorouracil (Carac)FDA LinkGeneric 06/2010 - 03/2008
2	Testosterone (Sustanon)FDA Link 02/2009 - 04/2006
2	Estramustine FDA Link 03/2007 - 12/2006
2	A-factor (Streptomyces)IBA 11/2006 - 11/2002
2	Indicators and Reagents (Reagents)IBA 11/2006 - 12/2003
2	InterferonsIBA 09/2006 - 01/2005
1	palbociclibIBA 01/2022
1	Thymidine KinaseIBA 01/2022
1	Sunitinib (Sutent)FDA Link 12/2021
1	ruxolitinibIBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	enzalutamideIBA 12/2020
1	CrizotinibIBA 12/2020

Therapy/Procedure

69	Therapeutics 03/2022 - 05/2003
22	Drug Therapy (Chemotherapy) 01/2022 - 05/2003
11	Prostatectomy (Retropubic Prostatectomy) 01/2017 - 11/2002
9	Radiotherapy 10/2020 - 09/2011
5	Neoadjuvant Therapy 03/2022 - 02/2008
5	Castration 12/2020 - 11/2009
4	Brachytherapy 11/2018 - 09/2011
3	Aftercare (After-Treatment) 01/2022 - 09/2011
2	Modified Radical Mastectomy (Mastectomy, Modified) 01/2020 - 09/2017
2	Adjuvant Chemotherapy 10/2016 - 02/2009
1	Blood Transfusion (Blood Transfusions) 01/2022
1	Length of Stay 01/2022
1	Mastectomy (Mammectomy) 01/2021
1	Mammaplasty (Breast Reconstruction) 01/2020